Process HPLC Column, RP C4, 10um, 100A. 50mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. The moderate hydrophobicity of the C4 ligand makes this stationary phase an excellent choice for purification of hydrophobic and neutral compounds while providing lower retention than C18 phases and greater retention than many C8 phases. The fully endcapped surface delivers reliable chromatographic performance and reproducible purification results in process-scale applications.
68004-P50-50 is a process HPLC column with dimensions of 50 mm ID x 50 mm length, packed with 10 µm RP C4 Butyl particles featuring a 100 Å pore size. The large internal diameter is designed for substantial sample loading and high-throughput purification, while the short 50 mm length is optimized for rapid purification cycles, process development, and manufacturing method screening. Typical flow rates are approximately 80–200 mL/min depending on system capabilities, mobile phase conditions, and process requirements.
This column is intended for in-process purification where target compounds are isolated and collected for further development, formulation, or production. The short bed length is particularly beneficial when throughput and cycle time are prioritized over maximum chromatographic resolution. Applications include pharmaceutical manufacturing support, synthetic chemistry, natural product purification, process optimization, and compound production workflows. A specialized process-scale HPLC system capable of high flow rates, large injection volumes, and fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C4 Butyl stationary phase
Fully double endcapped chemistry
Traditional butyl (C4) bonded phase
Designed for process-scale HPLC purification
High sample loading capacity
10 µm particles for lower operating backpressure
Suitable for high flow rates
Less retention than C18 columns
Fast purification cycles with 50 mm length
Excellent for process development and method optimization
Typical Applications
Process-scale HPLC purification
Small molecule isolation
Pharmaceutical manufacturing support
Synthetic chemistry
Natural product purification
Compound production
Process development
Method optimization
Manufacturing support
Fraction collection
Specifications
Product Type: Process HPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 50 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 80–200 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for purification rather than routine analytical HPLC
Used for isolation and collection of purified compounds
Suitable for process development and production-scale purification
Requires a process-scale HPLC system capable of high flow rates and fraction collection
Provides less retention than C18 phases and greater retention than many C8 phases
Short column length supports rapid purification and process optimization workflows
Special Order Item